One of the hotter debates going on in eyecare today is the compatibility of soft contact lens materials with the myriad of contact lens solutions available. Much research is being devoted to this topic. Additionally, concerns over the best product to fill the bowl of the rigid scleral lens still continues. Information for both the soft lens solutions and the scleral lens solutions are below.
The Staining Grid is an easy-to-use reference tool showing the level of biocompatibility of various contact
lens/multipurpose solutions. It appears as a "grid" with the solutions listed across the top and the lens
materials in the first column. The percentages which appear in each cell represent the average percentage
of the cornea which was stained 2 hours after lens/solution insertion. To choose a biocompatible multipurpose
solution for a particular lens brand:
1) Find the lens material (if it has been tested) in the first column of the grid.
2) Follow across that row and select a solution which results in minimal corneal staining (i.e., green zone).
Soft Lens and Solution Combinations
|
|||||||||||
| Color Key | 0% - 9% | ||||||||||
| 10% - 20% | |||||||||||
| Greater than 20% | |||||||||||
| Unisol 4 Saline |
Clear Care | Opti-Free Express |
Opti-Free Replenish |
Renu MoistureLoc |
Renu Multiplus |
Walmart MPS |
Target MPS |
Complete Moisture Plus |
Complete MPS |
Aquify | |
| Acuvue 2 | 1% | 1% | 2% | 5% | 25% | 1% | 1% | 1% | 2% | Testing Ongoing |
1% |
| Proclear | 1% | 1% | 1% | 2% | No Further Testing |
57% | 61% | 54% | 16% | Testing Ongoing |
12% |
| Soflens 66 | 1% | 1% | 1% | 1% | No Further Testing |
73% | 66% | 62% | 53% | Testing Ongoing |
8% |
| Acuvue Advance | 1% | 1% | 1% | 1% | No Further Testing |
13% | 16% | 13% | 20% | Testing Ongoing |
2% |
| Acuvue Oasys | 2% | 1% | 3% | 5% | 10% | 9% | 12% | 8% | 5% | Testing Ongoing |
3% |
| Biofinity | 2% | 2% | 3% | 2% | No Further Testing |
4% | 4% | 3% | 6% | Testing Ongoing |
2% |
| Purevision | 2% | 1% | 4% | 7% | 6% | 73% | 71% | 76% | 48% | 15% | 21% |
| O2 Optix | 2% | 1% | 2% | 5% | 7% | 24% | 41% | 28% | 18% | Testing Ongoing |
3% |
| Focus Night & Day | 2% | 1% | 2% | 3% | No Further Testing |
24% | 36% | 24% | 16% | 1% | 3% |
| H2O2 | Polyquad | Biguanides | |||||||||
Scleral Lens Filling Solutions |
||||
| 0.9% sodium chloride inhalation solution |
LacriPure (Menicon) |
ScleralFil (Bausch&Lomb) |
Purilens Plus (Purilens) |
Nutrifill (Nutrifill) |
| No buffers No preservatives |
No buffers No preservatives |
Contains buffers No preservatives |
Contains buffers No preservatives |
Contains buffers Contains electrolytes No preservatives |
| Off Label | FDA Approved | FDA Approved | FDA Approved | FDA Approved |
| 3ml or 5 ml | 5ml | 10ml | 4 ounce bottle | 10ml |
| Box of 100 Vials | Box of 98 Vials | Box of 30 Vials | Bottle Replaced Every 15 Days | Box of 35 Vials |
Additionally, the unsuspecting contact lens wearer may be susceptible to the generic solutions fluid in the bottle changing without warning. Between 2002 and 2007, three of the largest mass merchandisers and five of the largest drug store chains all changed the formula of their private label multipurpose solutions at least twice.
Solution and Lens Compatibility
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